INFORMED CONSENT RATES FOR NEONATAL RANDOMIZED CONTROLLED TRIALS IN LOW- AND LOWER MIDDLE-INCOME VERSUS HIGH-INCOME COUNTRIES: A SYSTEMATIC REVIEW.

Informed consent rates for neonatal randomized controlled trials in low- and lower middle-income versus high-income countries: A systematic review.

ObjectiveLegal, ethical, and regulatory requirements of medical research uniformly call for informed consent.We aimed to characterize and compare consent rates for neonatal randomized controlled trials in low- and lower middle-income countries versus high-income countries, and to evaluate the influence of study characteristics on consent rates.Meth

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Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP

IntroductionFentanyl and fentanyl analogs (F/FA) have become increasingly common adulterants in copyright prescription pills and illicit street drug mixtures ORG LENTILS CAN due to their ease of synthesis and exceedingly high potency.The ongoing epidemic of fatal overdoses fueled by F/FA continues to highlight the need for longer-acting therapies t

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Beneficial Changes in Growth Performance, Antioxidant Capacity, Immune Response, Hepatic Health, and Flesh Quality of Trachinotus ovatus Fed With Oedocladium carolinianum

The purpose of this study is to assess the feasibility of astaxanthin-rich Oedocladium carolinianum as an immunostimulant in the diet for Trachinotus ovatus.Three experimental diets containing 0% (OC0), 1% (OC1), and 5% (OC5) O.carolinianum powder were formulated for 6-week feeding trials.The results indicated that the OC5 diet boosted the growth p

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PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Summary: The RET proto-oncogene encodes receptor tyrosine kinase, expressed primarily in tissues of neural crest origin.De-regulation of RET signaling is implicated in several human cancers.Recent phosphatome interactome analysis identified PTPRA interacting with the neurotrophic factor (GDNF)-dependent RET-Ras-MAPK signaling-axis.Here, by identify

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